The Anatolian peninsula (also called Asia Minor), comprising most of modern Turkey, is one of the oldest continually inhabited regions in the world due to its location at the intersection of Asia and Europe. The earliest Neolithic settlements such as Çatalhöyük (Pottery Neolithic), Çayönü (Pre-Pottery Neolithic A to Pottery Neolithic), Nevali Cori (Pre-Pottery Neolithic B), Hacilar (Pottery Neolithic), Göbekli Tepe (Pre-Pottery Neolithic A) and Mersin are considered to be among the earliest human settlements in the world. The settlement of Troy starts in the Neolithic and continues into the Iron Age. Through recorded history, Anatolians have spoken Indo-European, Semitic and Kartvelian languages, as well as many languages of uncertain affiliation. In fact, given the antiquity of the Indo-European Hittite and Luwian languages, some scholars have proposed Anatolia as the hypothetical center from which the Indo-European languages have radiated.
The first major empire in the area was that of the Hittites, from the 18th through the 13th century BCE. Subsequently, the Phrygians, an Indo-European people, achieved ascendancy until their kingdom was destroyed by the Cimmerians in the 7th century BCE. The most powerful of Phrygia's successor states were Lydia, Caria and Lycia. The Lydians and Lycians spoke languages that were fundamentally Indo-European, but both languages had acquired non-Indo-European elements prior to the Hittite and Hellenic periods.
The west coast of Anatolia was meanwhile settled by the Ionians, one of the ancient Greek peoples. The entire area was conquered by the Persian Achaemenid Empire during the 6th and 5th centuries and later fell to Alexander the Great in 334 BCE. Anatolia was subsequently divided into a number of small Hellenistic kingdoms (including Bithynia, Cappadocia, Pergamum, and Pontus), all of which had succumbed to Rome by the mid-1st century BCE. In 324 CE, the Roman emperor Constantine I chose Byzantium to be the new capital of the Roman Empire, renaming it New Rome (later Constantinople and Istanbul). After the fall of the Western Roman Empire, it became the capital of the Byzantine Empire (Eastern Roman Empire).
Source: (Wikipedia & CIA Fact Book)